Discriminating anisometropic amblyopia from myopia based on interocular inhibition

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Discriminating anisometropic amblyopia from myopia based on interocular inhibition

Amblyopia screening during childhood is critical for early detection and successful treatment. In the current study, we develop and evaluate a screening method that exploits the imbalanced interocular inhibition between amblyopic and fellow eyes. In nineteen subjects with anisometropic amblyopia and twenty-two age-matched subjects with myopia, we measured the area under the contrast sensitivity...

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Deficient binocular combination reveals mechanisms of anisometropic amblyopia: signal attenuation and interocular inhibition.

Amblyopia is a developmental disorder that results in deficits of monocular and binocular vision. It is presently unclear whether these deficits result from attenuation of signals in the amblyopic eye, inhibition by signals in the fellow eye, or both. In this study, we characterize mechanisms underlying anisometropic amblyopia using a binocular phase and contrast combination paradigm and a cont...

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Anisometropic Amblyopia: Nonsurgical Treatment

Anisometropic amblyopia is characterized by a decrease in best corrected visual acuity in one eye as a result of significantly different refractive errors between the two eyes. The eye that ultimately provides a more blurred image to the visual cortex develops amblyopia.1 Several authors have suggested that anisometropia is the leading cause of amblyopia and is responsible for approximately 50%...

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Visual functions and interocular interactions in anisometropic children with and without amblyopia.

PURPOSE In uncorrected anisometropia, protracted dichoptic stimulation may result in interocular inhibition, which may be a contributing factor in amblyopia development. This study investigates the relationship between interocular interactions and anisometropic amblyopia. METHODS Three visual functions (low-contrast acuity, contrast sensitivity, and alignment sensitivity) were measured in the...

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Contour integration in anisometropic amblyopia

Contour integration was measured in a group of anisometropic amblyopes to test the idea recently put forward that positional uncertainty sets a fundamental limit to contour integration in amblyopia. Anisometropic amblyopia, unlike strabismic amblyopia, has little or no positional uncertainty once the initial filtering loss has been taken into account. Therefore, according to the explanation put...

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ژورنال

عنوان ژورنال: Vision Research

سال: 2015

ISSN: 0042-6989

DOI: 10.1016/j.visres.2015.02.003